Research spanning medicinal chemistry, pharmacokinetics, and
clinical practice, from peptide synthesis at the University of
Minnesota to current clinical research at Mayo Clinic.
Peer-reviewed publication
Ericson MD, Tran LT, Mathre SS, Freeman KT,
Holdaway K, John K, Lunzer MM, Bouchard JL, Haskell-Luevano C.
Discovery of a pan-melanocortin receptor antagonist
[Ac-DPhe(pI)-Arg-Nal(2′)-Orn-NH2] at the MC1R,
MC3R, MC4R, and MC5R that mediates an increased feeding response
in mice and a 40-fold selective MC1R antagonist
[Ac-DPhe(pI)-DArg-Nal(2′)-Arg-NH2].
J Med Chem. 2023;66(12):8103–8117.
doi:10.1021/acs.jmedchem.3c00432
Manuscripts in preparation
Steinke KA, Patel SP, Mathre SS, Sanders KA,
Soefje SA, Cole KC, Sandahl TB. Impact of premedication
de-escalation on the incidence of infusion-related reactions with
isatuximab. Target journal: JCO Oncology Practice.
Mathre SS, Siegel LR, Larsen BE, Wood C, Tetlie
AE, Wiste RM, Tinder A, Mackey RM. The impact of music therapy on
high-risk medication use in an inpatient palliative care setting.
Target journal: Journal of Pain and Symptom Management.
Research experience
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Haskell-Luevano Lab, UMN College of Pharmacy
· 2021; synthesized and purified melanocortin-4 receptor
analog tetrapeptides involved in obesity and appetite control;
contributed to the J Med Chem publication
above.
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Elmquist Lab, UMN College of Pharmacy ·
2020; built a pharmacokinetic model of drug redistribution
following hemodialysis.
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Farah Lab, UMN · 2018 – 2019; drafted
the pharmacokinetic study design for laser-assisted drug
delivery of minoxidil and directed the pharmacokinetics portion
of the resulting paper.
Also co-authored two Industry Pharmacists Organization analyses of
direct-to-industry job placement among PharmD graduates (2021),
presented to national IPhO leadership.
